VLDL Induces Adipocyte Differentiation in ApoE-Dependent Manner
نویسندگان
چکیده
منابع مشابه
VLDL induces adipocyte differentiation in ApoE-dependent manner.
OBJECTIVE To clarify the role of very low density lipoprotein (VLDL) and apolipoprotein E (apoE) in adipogenesis, we studied newly developed hyperlipidemic obese (ob/ob;apoE-/-) mice. Because hydrolysis of VLDL is believed to be the major source of adipogenic free fatty acids, a higher plasma level of VLDL in these mice should exaggerate obesity. METHODS AND RESULTS When fed a high-fat, high-...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2003
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.0000085040.58340.36